Mingyan Cao

A Quadrupole Dalton-based multi-attribute method for product characterization, process development, and quality control of therapeutic proteins

Weichen Xu, Rod Brian Jimenez, Rachel Mowery et al. · mAbs · 2017 · 70 citations · Full text

Product Characterization, Molecular Biology, Protein Purification +23

Effects of antibody disulfide bond reduction on purification process performance and final drug substance stability

Wai Keen Chung, Brian Russell, Yanhong Yang et al. · Biotechnology and Bioengineering · 2017 · 55 citations · Full text

A systematic approach for analysis and characterization of mispairing in bispecific antibodies with asymmetric architecture

Chunlei Wang, Bhargavi Vemulapalli, Mingyan Cao et al. · mAbs · 2018 · 49 citations · Full text

Cathepsin L Causes Proteolytic Cleavage of Chinese‐Hamster‐Ovary Cell Expressed Proteins During Processing and Storage: Identification, Characterization, and Mitigation

Haibin Luo, Tie Liu, Mingyan Cao et al. · Biotechnology Progress · 2018 · 44 citations · Full text

Cation Exchange, Chinese‐hamster‐ovary Cell, Glycobiology +23

Site-specific antibody-drug conjugate heterogeneity characterization and heterogeneity root cause analysis

Mingyan Cao, Niluka De Mel, Yang Jiao et al. · mAbs · 2019 · 43 citations · Full text

Drug Target, Immunocytochemical Technique, Immunology +21