Niluka De Mel

Site-specific antibody-drug conjugate heterogeneity characterization and heterogeneity root cause analysis

Mingyan Cao, Niluka De Mel, Yang Jiao et al. · mAbs · 2019 · 50 citations · Full text

Pharmacy, Biochemistry, Molecular Biology +17

Characterization of IgG1 Fc Deamidation at Asparagine 325 and Its Impact on Antibody-dependent Cell-mediated Cytotoxicity and FcγRIIIa Binding

Xiaojun Lu, LeeAnn Machiesky, Niluka De Mel et al. · Scientific Reports · 2020 · 47 citations · Full text

Pharmacy, Biochemistry, Immunology +17

Charge variants characterization and release assay development for co-formulated antibodies as a combination therapy

Mingyan Cao, Niluka De Mel, A. G. Shannon et al. · mAbs · 2019 · 37 citations · Full text

Pharmacy, Pharmaceutical Biotechnology, Pharmacology +17

Analytical characterization of coformulated antibodies as combination therapy

Jun Kim, Yoen Joo Kim, Mingyan Cao et al. · mAbs · 2020 · 32 citations · Full text

Pharmacy, Pharmaceutical Analysis, Pharmaceutics +17

Characterization of N-Terminal Glutamate Cyclization in Monoclonal Antibody and Bispecific Antibody Using Charge Heterogeneity Assays and Hydrophobic Interaction Chromatography

Mingyan Cao, Niluka De Mel, Jihong Wang et al. · Journal of Pharmaceutical Sciences · 2021 · 17 citations · Full text

Pharmacy, Biochemistry, Pharmaceutics +17