Feroz R. Papa

IRE1α Induces Thioredoxin-Interacting Protein to Activate the NLRP3 Inflammasome and Promote Programmed Cell Death under Irremediable ER Stress

Alana G. Lerner, John-Paul Upton, Paurush Praveen et al. · Cell Metabolism · 2012 · 812 citations · Full text

Inflammation, Irremediable Er Stress, Signal Transduction +11

IRE1α Kinase Activation Modes Control Alternate Endoribonuclease Outputs to Determine Divergent Cell Fates

Dan Han, Alana G. Lerner, Lieselotte Vande Walle et al. · Cell · 2009 · 798 citations · Full text

Transcriptional Regulation, Signal Transduction, Divergent Cell Fates +11

IRE1α Cleaves Select microRNAs During ER Stress to Derepress Translation of Proapoptotic Caspase-2

John-Paul Upton, Likun Wang, Dan Han et al. · Science · 2012 · 632 citations · Full text

On the mechanism of sensing unfolded protein in the endoplasmic reticulum

Joel J. Credle, Janet Finer-Moore, Feroz R. Papa et al. · Proceedings of the National Academy of Sciences · 2005 · 572 citations · Full text

Allosteric Inhibition of the IRE1α RNase Preserves Cell Viability and Function during Endoplasmic Reticulum Stress

Rajarshi Ghosh, Likun Wang, Eric S. Wang et al. · Cell · 2014 · 473 citations · Full text

Reductive Stress, Allosteric Inhibition, Molecular Regulation +9