Ashley J. Chui

DPP8/DPP9 inhibitor-induced pyroptosis for treatment of acute myeloid leukemia

Darren C. Johnson, Cornelius Y. Taabazuing, Marian C. Okondo et al. · Nature Medicine · 2018 · 347 citations · Full text

Hematological Malignancy, Oncology, Dpp8/dpp9 Inhibitor-induced Pyroptosis +6

DPP8 and DPP9 inhibition induces pro-caspase-1-dependent monocyte and macrophage pyroptosis

Marian C. Okondo, Darren C. Johnson, Ramya Sridharan et al. · Nature Chemical Biology · 2016 · 300 citations · Full text

Inflammation, Signal Transduction, Apoptosis +9

N-terminal degradation activates the NLRP1B inflammasome

Ashley J. Chui, Marian C. Okondo, Sahana D. Rao et al. · Science · 2019 · 288 citations · Full text

Apoptosis, Immunology, Nlrp1b N Terminus +20

Inhibition of Dpp8/9 Activates the Nlrp1b Inflammasome

Marian C. Okondo, Sahana D. Rao, Cornelius Y. Taabazuing et al. · Cell chemical biology · 2018 · 197 citations · Full text

Inflammation, Anti-inflammatory, Signal Transduction +8

DPP8/9 inhibitors are universal activators of functional NLRP1 alleles

Kuo Gai, Marian C. Okondo, Sahana D. Rao et al. · Cell Death and Disease · 2019 · 91 citations · Full text