Chuan Ye

The microbial metabolite agmatine acts as an FXR agonist to promote polycystic ovary syndrome in female mice

Chuyu Yun, Sen Yan, Baoying Liao et al. · Nature Metabolism · 2024 · 80 citations

Medicine, Biochemistry, Endocrinology +8

A microbial metabolite inhibits the HIF-2α-ceramide pathway to mediate the beneficial effects of time-restricted feeding on MASH

Yi Zhang, Xuemei Wang, Jun Lin et al. · Cell Metabolism · 2024 · 52 citations

Life Sciences, Biochemistry, Nutritional Sciences +12

A microbial amino-acid-conjugated bile acid, tryptophan-cholic acid, improves glucose homeostasis via the orphan receptor MRGPRE

Jun Lin, Qixing Nie, Jie Cheng et al. · Cell · 2025 · 46 citations

Life Sciences, Biochemistry, Molecular Biology +17

Metabolic signaling of ceramides through the FPR2 receptor inhibits adipocyte thermogenesis

Hui Lin, Chuanshun Ma, Kui Cai et al. · Science · 2025 · 40 citations

Life Sciences, Biochemistry, Molecular Biology +17

Candida albicans accelerates atherosclerosis by activating intestinal hypoxia-inducible factor2α signaling

Xuemei Wang, Shuang Zhou, Xiaomin Hu et al. · Cell Host & Microbe · 2024 · 39 citations · Full text

Life Sciences, Immunology, Microbiology +14