Zihong Chen

Regulation of IRF-3-dependent Innate Immunity by the Papain-like Protease Domain of the Severe Acute Respiratory Syndrome Coronavirus

Santhana G. Devaraj, Nan Wang, Zhongbin Chen et al. · Journal of Biological Chemistry · 2007 · 418 citations · Full text

Innate Immune System, Viral Pathogenesis, Immunology +17

Distinct Poly(I-C) and Virus-activated Signaling Pathways Leading to Interferon-β Production in Hepatocytes

Kui Li, Zihong Chen, Nobuyuki Kato et al. · Journal of Biological Chemistry · 2005 · 360 citations · Full text

Viral Replication, Innate Immune System, Immunology +26

Quercetin Attenuates Inflammatory Responses in BV-2 Microglial Cells: Role of MAPKs on the Nrf2 Pathway and Induction of Heme Oxygenase-1

Grace Y. Sun, Zihong Chen, Kimberly J. Jasmer et al. · PLoS ONE · 2015 · 175 citations · Full text

Lipid Peroxidation, Immunology, Immune Regulation +21

GB Virus B Disrupts RIG-I Signaling by NS3/4A-Mediated Cleavage of the Adaptor Protein MAVS

Zihong Chen, Yann Bénureau, René Rijnbrand et al. · Journal of Virology · 2006 · 136 citations · Full text

Viral Replication, Adaptor Protein Mavs, Molecular Virology +15

Ubiquitination and proteasomal degradation of interferon regulatory factor-3 induced by Npro from a cytopathic bovine viral diarrhea virus

Zihong Chen, René Rijnbrand, Rohit K. Jangra et al. · Virology · 2007 · 123 citations · Full text

Interferon Regulatory Factor-3, Viral Replication, Proteasomal Degradation +8