Herbert Spapen

Efficacy and Safety of Tifacogin (Recombinant Tissue Factor Pathway Inhibitor) in Severe Sepsis

Edward Abraham, Konrad Reinhart, Steven M. Opal et al. · JAMA · 2003 · 951 citations

High-volume versus standard-volume haemofiltration for septic shock patients with acute kidney injury (IVOIRE study): a multicentre randomized controlled trial

Olivier Joannès-Boyau, Patrick M. Honoré, Paul Perez et al. · Intensive Care Medicine · 2013 · 412 citations

Acute Care, Patient Safety, Sepsis +6

Insufficient β-lactam concentrations in the early phase of severe sepsis and septic shock

Fabio Silvio Taccone, Pierre‐François Laterre, Thierry Dugernier et al. · Critical Care · 2010 · 363 citations · Full text

Cardiac Troponins I and T Are Biological Markers of Left Ventricular Dysfunction in Septic Shock

Kristien M. ver Elst, Herbert Spapen, Duc Nam Nguyen et al. · Clinical Chemistry · 2000 · 323 citations

Renal and neurological side effects of colistin in critically ill patients

Herbert Spapen, Rita Jacobs, Viola Van Gorp et al. · Annals of Intensive Care · 2011 · 276 citations · Full text