Jacob E. Simpson

Novel phenolic antioxidants as multifunctional inhibitors of inducible VCAM-1 expression for use in atherosclerosis

Charles Q. Meng, Patricia K. Somers, Carolyn L. Rachita et al. · Bioorganic & Medicinal Chemistry Letters · 2002 · 57 citations · Full text

Vascular Disease, Cardiovascular Disease, Biochemistry +11

Carboxylated, Heteroaryl-Substituted Chalcones as Inhibitors of Vascular Cell Adhesion Molecule-1 Expression for Use in Chronic Inflammatory Diseases

Charles Q. Meng, Liming Ni, Kimberly J. Worsencroft et al. · Journal of Medicinal Chemistry · 2007 · 48 citations

Discovery of Novel Phenolic Antioxidants as Inhibitors of Vascular Cell Adhesion Molecule-1 Expression for Use in Chronic Inflammatory Diseases

Charles Q. Meng, Patricia K. Somers, Lee K. Hoong et al. · Journal of Medicinal Chemistry · 2004 · 28 citations · Full text

Inflammation, Chronic Inflammatory Diseases, Medicinal Chemistry +14

Discovery of novel heteroaryl-substituted chalcones as inhibitors of TNF-α-induced VCAM-1 expression

Charles Q. Meng, Xiaoxiang Zheng, Liming Ni et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 24 citations · Full text

Novel Heteroaryl-substituted Chalcones, Tnf-α-induced Vcam-1 Expression, Medicinal Chemistry +6

Synthesis of an aminopropyl analog of the experimental anticancer drug tallimustine, and activation of its 4-nitrobenzylcarbamoyl prodrug by nitroreductase and NADH

Moses Lee, Jacob E. Simpson, Shirley Woo et al. · Bioorganic & Medicinal Chemistry Letters · 1997 · 18 citations

Medicinal Chemistry, Biochemistry, Medicine +9