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Synthesis of an aminopropyl analog of the experimental anticancer drug tallimustine, and activation of its 4-nitrobenzylcarbamoyl prodrug by nitroreductase and NADH

Medicinal ChemistryBiochemistryMedicineNatural SciencesAminopropyl Analog4-Nitrobenzylcarbamoyl ProdrugPharmacological AgentPharmacotherapyAnti-cancer AgentDrug DevelopmentPharmacologyDrug Discovery