Theresa R. Phillips

Discovery of (2,4-Dihydroxy-5-isopropylphenyl)-[5-(4-methylpiperazin-1-ylmethyl)-1,3-dihydroisoindol-2-yl]methanone (AT13387), a Novel Inhibitor of the Molecular Chaperone Hsp90 by Fragment Based Drug Design

Andrew Woodhead, Hayley C. Angove, Maria G. Carr et al. · Journal of Medicinal Chemistry · 2010 · 258 citations

Pharmaceutical Science, Novel Inhibitor, Drug Target +19

Fragment-Based Drug Discovery Applied to Hsp90. Discovery of Two Lead Series with High Ligand Efficiency

Christopher W. Murray, Maria G. Carr, Owen Callaghan et al. · Journal of Medicinal Chemistry · 2010 · 185 citations · Full text

Molecular Docking, High Ligand Efficiency, Medicinal Chemistry +15

Debenzylation using catalytic hydrogenolysis in trifluoroethanol, and the total synthesis of (−)-raumacline

Patrick D. Bailey, Mark A. Beard, Hoa P.T. Dang et al. · Tetrahedron Letters · 2008 · 28 citations

Chemical Engineering, Engineering, Catalytic Hydrogenolysis +6

Unexpected cis selectivity in the Pictet–Spengler reaction

Patrick D. Bailey, Mark A. Beard, Theresa R. Phillips · Tetrahedron Letters · 2009 · 27 citations

Reaction Intermediate, Cis Selectivity, Chemistry

Synthesis and evaluation of a novel series of indoloisoquinolines as small molecule anti-malarial leads

Paul Horrocks, Samantha Fallon, Laura Denman et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 21 citations

Medicinal Chemistry, Novel Series, Biochemistry +8