Emmanuel Gautherot

In vitro and in vivo targeting of radiolabeled monovalent and divalent haptens with dual specificity monoclonal antibody conjugates: enhanced divalent hapten affinity for cell-bound antibody conjugate.

J M Le Doussal, Meghan Martin, Emmanuel Gautherot et al. · PubMed · 1989 · 153 citations

Immunocytochemical Technique, Vivo Targeting, Immunology +16

Targeting of indium 111-labeled bivalent hapten to human melanoma mediated by bispecific monoclonal antibody conjugates: imaging of tumors hosted in nude mice.

J M Le Doussal, Anne Gruaz‐Guyon, Meghan Martin et al. · PubMed · 1990 · 108 citations

Engineering, Immunology, Immunotherapy +20

Radioimmunotherapy in medullary thyroid cancer using bispecific antibody and iodine 131-labeled bivalent hapten: preliminary results of a phase I/II clinical trial.

Françoise Kraeber‐Bodéré, Stéphane Bardet, Cornelis A. Hoefnagel et al. · PubMed · 1999 · 105 citations

Pharmacotherapy, Immunotherapy, Tumor Biology +18

Bispecific monoclonal antibody-mediated targeting of an indium-111-labeled DTPA dimer to primary colorectal tumors: pharmacokinetics, biodistribution, scintigraphy and immune response.

J M Le Doussal, A. Chetanneau, Anne Gruaz‐Guyon et al. · PubMed · 1993 · 84 citations

Surgical Oncology, Immunology, Immunotherapy +18

Pharmacokinetic study of anti-interleukin-6 (IL-6) therapy with monoclonal antibodies: enhancement of IL-6 clearance by cocktails of anti-IL-6 antibodies

FA Montero-Julian, Bernard Klein, Emmanuel Gautherot et al. · Blood · 1995 · 83 citations · Full text