J M Le Doussal

In vitro and in vivo targeting of radiolabeled monovalent and divalent haptens with dual specificity monoclonal antibody conjugates: enhanced divalent hapten affinity for cell-bound antibody conjugate.

J M Le Doussal, Meghan Martin, Emmanuel Gautherot et al. · PubMed · 1989 · 153 citations

Immunocytochemical Technique, Vivo Targeting, Immunology +16

Targeting of indium 111-labeled bivalent hapten to human melanoma mediated by bispecific monoclonal antibody conjugates: imaging of tumors hosted in nude mice.

J M Le Doussal, Anne Gruaz‐Guyon, Meghan Martin et al. · PubMed · 1990 · 108 citations

Engineering, Immunology, Immunotherapy +20

Radioimmunodetection of medullary thyroid cancer using a bispecific anti-CEA/anti-indium-DTPA antibody and an indium-111-labeled DTPA dimer.

P Peltier, C. Curtet, J.F. Chatal et al. · PubMed · 1993 · 87 citations

Pathology, Immunotherapy, 111In-labeled Dtpa Dimer +16

Bispecific monoclonal antibody-mediated targeting of an indium-111-labeled DTPA dimer to primary colorectal tumors: pharmacokinetics, biodistribution, scintigraphy and immune response.

J M Le Doussal, A. Chetanneau, Anne Gruaz‐Guyon et al. · PubMed · 1993 · 84 citations

Surgical Oncology, Immunology, Immunotherapy +18

Pretargeted radioimmunotherapy of human colorectal xenografts with bispecific antibody and 131I-labeled bivalent hapten.

Emmanuel Gautherot, Éric Rouvier, Laurent Daniel et al. · PubMed · 2000 · 75 citations