Chunze Li

Kinesin Spindle Protein (KSP) Inhibitors. 9. Discovery of (2<i>S</i>)-4-(2,5-Difluorophenyl)-<i>N</i>-[(3<i>R</i>,4<i>S</i>)-3-fluoro-1-methylpiperidin-4-yl]-2-(hydroxymethyl)-<i>N</i>-methyl-2-phenyl-2,5-dihydro-1<i>H</i>-pyrrole-1-carboxamide (MK-0731) for the Treatment of Taxane-Refractory Cancer

Christopher D. Cox, Paul J. Coleman, Michael J. Breslin et al. · Journal of Medicinal Chemistry · 2008 · 156 citations · Full text

Mechanistic Studies on the Bioactivation of Diclofenac:  Identification of Diclofenac-<i>S</i>-acyl-glutathione in Vitro in Incubations with Rat and Human Hepatocytes

Mark P. Grillo, Fengmei Hua, Charles G. Knutson et al. · Chemical Research in Toxicology · 2003 · 82 citations

Discovery of the Highly Potent PI3K/mTOR Dual Inhibitor PF-04979064 through Structure-Based Drug Design

Hengmiao Cheng, Chunze Li, Simon Bailey et al. · ACS Medicinal Chemistry Letters · 2012 · 78 citations · Full text

Drug Target, Pharmaceutical Chemistry, Empirical Scaling Tool +18

Population pharmacokinetic and exposure–response analysis for trastuzumab administered using a subcutaneous “manual syringe” injection or intravenously in women with HER2-positive early breast cancer

Angelica Quartino, Carina Hillenbach, Jing Li et al. · Cancer Chemotherapy and Pharmacology · 2015 · 72 citations · Full text

Comparative Effects of Fibrates on Drug Metabolizing Enzymes in Human Hepatocytes

Thomayant Prueksaritanont, Karen Richards, Yue Qiu et al. · Pharmaceutical Research · 2005 · 71 citations

Health Sciences, Biochemistry, Pharmacological Study +15