Spherical aggregates of β-amyloid (amylospheroid) show high neurotoxicity and activate tau protein kinase I/glycogen synthase kinase-3β

Minako Hoshi, Michio Sato, Shinichiro Matsumoto, +4

Proceedings of the National Academy of Sciences

Regulation of mitochondrial pyruvate dehydrogenase activity by tau protein kinase I/glycogen synthase kinase 3beta in brain.

Minako Hoshi, Akihiko Takashima, Kei Noguchi, +7

Proceedings of the National Academy of Sciences

MitophagyApoptosisCell DeathMitochondrial BiologyTau Protein +20

Isolation and Characterization of Patient-derived, Toxic, High Mass Amyloid β-Protein (Aβ) Assembly from Alzheimer Disease Brains

Akihiko Noguchi, Satoko Matsumura, Mari Dezawa, +18

Journal of Biological Chemistry

Neurodegenerative DiseasesAlzheimer's DiseaseDegenerative PathologyNeurochemical BiomarkersProtein Misfolding +6

Na, K-ATPase α3 is a death target of Alzheimer patient amyloid-β assembly

Takayuki Ohnishi, Masako Yanazawa, Tomoya Sasahara, +32

Proceedings of the National Academy of Sciences

Two Distinct Amyloid β-Protein (Aβ) Assembly Pathways Leading to Oligomers and Fibrils Identified by Combined Fluorescence Correlation Spectroscopy, Morphology, and Toxicity Analyses

Satoko Matsumura, Keiko Shinoda, Mayumi Yamada, +20

Journal of Biological Chemistry

Aging- and obesity-related peri-muscular adipose tissue accelerates muscle atrophy

Shunshun Zhu, Zhe Tian, Daisuke Torigoe, +9

PLoS ONE

ObesityMetabolic SyndromeAtrophy Severity IncreasesMuscle FunctionBody Composition +13

Electron microscopic observation and single-stranded DNA binding activity of the Mcm4,6,7 complex

Michio Sato, Takahiro Gotow, Zhiying You, +5

Journal of Molecular Biology

BiochemistryMcm4,6,7 ComplexNatural SciencesElectron Microscopic ObservationOligonucleotide +4

Effects of professional oral health care on reducing the risk of chemotherapy-induced oral mucositis

Hirokazu Saito, Yutaka Watanabe, Kazumichi Sato, +5

Supportive Care in Cancer

OncologyOral CavityPatient SafetyOral HygieneOutcomes Research +6

The lncRNA Caren antagonizes heart failure by inactivating DNA damage response and activating mitochondrial biogenesis

Michio Sato, Tsuyoshi Kadomatsu, Keishi Miyata, +19

Nature Communications

An Artificial Esophagus Constructed of Cultured Human Esophageal Epithelial Cells, Fibroblasts, Polyglycolic Acid Mesh, and Collagen

Hirotaka Miki, Nobutoshi Ando, Soji Ozawa, +3

ASAIO Journal