Tomoya Sasahara

Na, K-ATPase α3 is a death target of Alzheimer patient amyloid-β assembly

Takayuki Ohnishi, Masako Yanazawa, Tomoya Sasahara et al. · Proceedings of the National Academy of Sciences · 2015 · 136 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

NMR-based site-resolved profiling of β-amyloid misfolding reveals structural transitions from pathologically relevant spherical oligomer to fibril

Yiling Xiao, Isamu Matsuda, Masafumi Inoue et al. · Journal of Biological Chemistry · 2019 · 31 citations · Full text

Life Sciences, Molecular Biology, Neurobiology +17

Alzheimer Aβ Assemblies Accumulate in Excitatory Neurons upon Proteasome Inhibition and Kill Nearby NAKα3 Neurons by Secretion

Hitomi Komura, Shota Kakio, Tomoya Sasahara et al. · iScience · 2019 · 19 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Na+/H+ exchanger inhibitor induces vasorelaxation through nitric oxide production in endothelial cells via intracellular acidification-associated Ca2+ mobilization

Tomoya Sasahara, Katsutoshi Yayama, Toshihiro Matsuzaki et al. · Vascular Pharmacology · 2012 · 18 citations

Life Sciences, Cell Biology, Pharmacology +16

Alzheimer's Aβ assembly binds sodium pump and blocks endothelial NOS activity via ROS-PKC pathway in brain vascular endothelial cells

Tomoya Sasahara, Kaori Satomura, Mari Tada et al. · iScience · 2021 · 17 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17