Long-term functional maintenance of primary human hepatocytes in vitro

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Science

Natural triterpenoids from licorice potently inhibit SARS-CoV-2 infection

Yi Yang, Junhua Li, Xinyuan Lai, +14

Journal of Advanced Research

A robust cell culture system supporting the complete life cycle of hepatitis B virus

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Scientific Reports

Effects of amino acid substitutions in hepatitis B virus surface protein on virion secretion, antigenicity, HBsAg and viral DNA

Kuanhui Xiang, Eleftherios Michailidis, Hai Ding, +10

Journal of Hepatology

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Pan-Genotype Hepatitis E Virus Replication in Stem Cell–Derived Hepatocellular Systems

Xianfang Wu, Viet Loan Dao Thi, Peng Liu, +6

Gastroenterology

Viral ReplicationMolecular VirologyHepatologyViral HepatitisImmunology +6

A two-step lineage reprogramming strategy to generate functionally competent human hepatocytes from fibroblasts

Bingqing Xie, Da Sun, Yuanyuan Du, +23

Cell Research

The effect of whey protein on viral infection and replication of SARS-CoV-2 and pangolin coronavirus in vitro

Huahao Fan, Bixia Hong, Yuqian Luo, +11

Signal Transduction and Targeted Therapy

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Naturally Occurring Deletions/Insertions in HBV Core Promoter Tend to Decrease in Hepatitis B e Antigen-Positive Chronic Hepatitis B Patients during Antiviral Therapy

Yaqin Peng, Baoming Liu, Jinlin Hou, +7

Antiviral Therapy

Identified human breast milk compositions effectively inhibit SARS-CoV-2 and variants infection and replication

Xinyuan Lai, Yanying Yu, Wei Xian, +11

iScience

TRIM56 impairs HBV infection and replication by inhibiting HBV core promoter activity

Xing Tian, Huijun Dong, Xinyuan Lai, +14

Antiviral Research

Viral ReplicationMolecular VirologyViral PersistencePathogenesisViral Pathogenesis +5