Francesca Sorrentino

Emerging Protein Targets for Anticancer Metallodrugs: Inhibition of Thioredoxin Reductase and Cathepsin B by Antitumor Ruthenium(II)−Arene Compounds

Angela Casini, Chiara Gabbiani, Francesca Sorrentino et al. · Journal of Medicinal Chemistry · 2008 · 265 citations · Full text

Medicinal Chemistry, Protein Targets, Representative Rapta +15

Cancer cell death induced by phosphine gold(I) compounds targeting thioredoxin reductase

Valentina Gandin, Aristi P. Fernandes, Maria Pia Rigobello et al. · Biochemical Pharmacology · 2009 · 249 citations · Full text

Biochemistry, Cancer Cell Death, Medicine +10

Anticancer Therapeutics That Target Selenoenzymes: Synthesis, Characterization, in vitro Cytotoxicity, and Thioredoxin Reductase Inhibition of a Series of Gold(I) Complexes Containing Hydrophilic Phosphine Ligands

Elena Vergara, Angela Casini, Francesca Sorrentino et al. · ChemMedChem · 2009 · 120 citations · Full text

Thioredoxin reductase, an emerging target for anticancer metallodrugs. Enzyme inhibition by cytotoxic gold(iii) compounds studied with combined mass spectrometry and biochemical assays

Chiara Gabbiani, Guido Mastrobuoni, Francesca Sorrentino et al. · MedChemComm · 2010 · 107 citations · Full text

Redox Signaling, Biological Inorganic Chemistry, Biochemistry +15

Activity of Rat Cytosolic Thioredoxin Reductase Is Strongly Decreased by <i>trans</i>-[Bis(2-amino-5- methylthiazole)tetrachlororuthenate(III)]:  First Report of Relevant Thioredoxin Reductase Inhibition for a Ruthenium Compound

Pasquale Mura, Mercedes Camalli, Alberto Bindoli et al. · Journal of Medicinal Chemistry · 2007 · 50 citations

Chemoprevention Strategy, 2-Amino-5- Methylthiazole, Chemical Biology +18