Andrew J. Theobald

Type IIA topoisomerase inhibition by a new class of antibacterial agents

B.D. Bax, Pan F. Chan, Drake S. Eggleston et al. · Nature · 2010 · 803 citations

Antibacterial Agents, Medicinal Chemistry, Inhibitory Activity +14

Structural basis of DNA gyrase inhibition by antibacterial QPT-1, anticancer drug etoposide and moxifloxacin

Pan F. Chan, Srikannathasan Velupillai, Jianzhong Huang et al. · Nature Communications · 2015 · 153 citations · Full text

Crystallization and initial crystallographic analysis of covalent DNA-cleavage complexes of <i>Staphyloccocus aureus</i> DNA gyrase with QPT-1, moxifloxacin and etoposide

Srikannathasan Velupillai, Alexandre Wohlkönig, Anthony Shillings et al. · Acta Crystallographica Section F Structural Biology Communications · 2015 · 23 citations · Full text

Covalent Dna-cleavage Complexes, Molecular Biology, Analytical Ultracentrifugation +16

Discovery and Biochemical Characterization of <i>Plasmodium</i> Thioredoxin Reductase Inhibitors from an Antimalarial Set

Andrew J. Theobald, Iván Caballero, Isabel Coma et al. · Biochemistry · 2012 · 18 citations

Phytoalexin, Medicinal Chemistry, Biochemical Characterization +13

High-yield production and characterization of biologically active GST-tagged human topoisomerase IIα protein in insect cells for the development of a high-throughput assay

Praveen Kumar Singh, Pan F. Chan, Martin Hibbs et al. · Protein Expression and Purification · 2010 · 14 citations

Biosynthesis, Engineering, Insect Cells +6