CIP2A Causes Tau/APP Phosphorylation, Synaptopathy, and Memory Deficits in Alzheimer’s Disease

Yang-Ping Shentu, Yuda Huo, Xiao-Long Feng, +12

Cell Reports

The deubiquitinating enzyme <scp>USP</scp>46 regulates <scp>AMPA</scp> receptor ubiquitination and trafficking

Yuda Huo, Natasha Khatri, Qingming Hou, +3

Journal of Neurochemistry

Protein UbiquitinationMolecular BiologyNeurotransmissionSynaptic SignalingCellular Physiology +19

The Autism Protein Ube3A/E6AP Remodels Neuronal Dendritic Arborization via Caspase-Dependent Microtubule Destabilization

Natasha Khatri, James Gilbert, Yuda Huo, +4

Journal of Neuroscience

Amyloid-β Induces AMPA Receptor Ubiquitination and Degradation in Primary Neurons and Human Brains of Alzheimer’s Disease

Yanmin Zhang, Ouyang Guo, Yuda Huo, +2

Journal of Alzheimer s Disease

Cysteine Oxidation Reactions Catalyzed by a Mononuclear Non-heme Iron Enzyme (OvoA) in Ovothiol Biosynthesis

Heng Song, Ampon Sae Her, Fiona Raso, +3

Organic Letters

BiosynthesisAldo-keto ReductaseBiochemistryMedicineBiocatalysis +11

PinX1 Is a Novel Microtubule-binding Protein Essential for Accurate Chromosome Segregation

Kai Yuan, Na Li, Kai Jiang, +11

Journal of Biological Chemistry

ChromatinGeneticsChromosome BiologyMolecular GeneticsCytoskeleton +4

Chromatin Protein HP1α Interacts with the Mitotic Regulator Borealin Protein and Specifies the Centromere Localization of the Chromosomal Passenger Complex

Xing Liu, Zhenwei Song, Yuda Huo, +11

Journal of Biological Chemistry

GeneticsMolecular BiologyMolecular GeneticsCytoskeletonCell Cycle +22

CIP2A-promoted astrogliosis induces AD-like synaptic degeneration and cognitive deficits

Yangping Shentu, Wenting Hu, Qing Zhang, +11

Neurobiology of Aging

Alzheimer's DiseaseMedicineBrain-immune InteractionCognitive DeficitsNeurology +5

Recruitment of separase to mitotic chromosomes is regulated by Aurora B

Kai Yuan, Na Li, Yuda Huo, +5

Cell Cycle

Role of the DUB enzyme USP7 in dendritic arborization, neuronal migration, and autistic-like behaviors in mice

Hui Qiao, Yuan Tian, Yuda Huo, +1

iScience