Concepedia

Sreekanth Kokkonda

SK

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Publications

13

Citations

1.1K

H-Index

13

Active since

2011

Affiliations

University of Washington(Current)

Monash University

Medicines for Malaria Venture

The University of Texas Southwestern Medical Center

Syngene International (India)

Sreekanth Kokkonda is an author at University of Washington specializing in drug discovery, malaria, and medicine.

Top concepts

Publications per year

2011–2022

13

Publications

13

A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria

Margaret A. Phillips, Julie Lotharius, Kennan C. Marsh et al. · Science Translational Medicine · 2015 · 367 citations

Structure-Guided Lead Optimization of Triazolopyrimidine-Ring Substituents Identifies Potent<i>Plasmodium falciparum</i>Dihydroorotate Dehydrogenase Inhibitors with Clinical Candidate Potential

José M. Coterón, María Marco, Jorge Esquivias et al. · Journal of Medicinal Chemistry · 2011 · 280 citations · Full text

Fluorine Modulates Species Selectivity in the Triazolopyrimidine Class of <i>Plasmodium falciparum</i> Dihydroorotate Dehydrogenase Inhibitors

Xiaoyi Deng, Sreekanth Kokkonda, Farah El Mazouni et al. · Journal of Medicinal Chemistry · 2014 · 109 citations · Full text

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A Triazolopyrimidine-Based Dihydroorotate Dehydrogenase Inhibitor with Improved Drug-like Properties for Treatment and Prevention of Malaria

Margaret A. Phillips, Karen L. White, Sreekanth Kokkonda et al. · ACS Infectious Diseases · 2016 · 85 citations · Full text

Bioisosteric Transformations and Permutations in the Triazolopyrimidine Scaffold To Identify the Minimum Pharmacophore Required for Inhibitory Activity against<i>Plasmodium falciparum</i>Dihydroorotate Dehydrogenase

Alka Marwaha, John White, Farah El Mazouni et al. · Journal of Medicinal Chemistry · 2012 · 69 citations · Full text

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