Ewan M. Smith

The Tuberous Sclerosis Protein TSC2 Is Not Required for the Regulation of the Mammalian Target of Rapamycin by Amino Acids and Certain Cellular Stresses

Ewan M. Smith, Stephen G. FINN, Andrew R. Tee et al. · Journal of Biological Chemistry · 2005 · 355 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Repurposed drugs targeting eIF2α-P-mediated translational repression prevent neurodegeneration in mice

Mark Halliday, Helois Radford, Karlijn A. M. Zents et al. · Brain · 2017 · 295 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

La-related Protein 1 (LARP1) Represses Terminal Oligopyrimidine (TOP) mRNA Translation Downstream of mTOR Complex 1 (mTORC1)

Bruno D. Fonseca, Chadi Zakaria, Jian-Jun Jia et al. · Journal of Biological Chemistry · 2015 · 276 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

PRAS40 Is a Target for Mammalian Target of Rapamycin Complex 1 and Is Required for Signaling Downstream of This Complex

Bruno D. Fonseca, Ewan M. Smith, Vivian H.-Y. Lee et al. · Journal of Biological Chemistry · 2007 · 238 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

Drosha drives the formation of DNA:RNA hybrids around DNA break sites to facilitate DNA repair

Wei-Ting Lu, Ben R Hawley, George Skalka et al. · Nature Communications · 2018 · 218 citations · Full text

Life Sciences, Genetics, Molecular Biology +17