Jorge Iván Castillo-Quan

Lithium Promotes Longevity through GSK3/NRF2-Dependent Hormesis

Jorge Iván Castillo-Quan, Li Li, Kerri J. Kinghorn et al. · Cell Reports · 2016 · 190 citations · Full text

Loss of<i>PLA2G6</i>leads to elevated mitochondrial lipid peroxidation and mitochondrial dysfunction

Kerri J. Kinghorn, Jorge Iván Castillo-Quan, Fernando Benito Bartolomé et al. · Brain · 2015 · 184 citations · Full text

From white to brown fat through the PGC-1α-dependent myokine irisin: implications for diabetes and obesity

Jorge Iván Castillo-Quan · Disease Models & Mechanisms · 2012 · 164 citations · Full text

Pgc-1α-dependent Myokine Irisin, Cellular Physiology, Insulin Signaling +22

A<i>Drosophila</i>Model of Neuronopathic Gaucher Disease Demonstrates Lysosomal-Autophagic Defects and Altered mTOR Signalling and Is Functionally Rescued by Rapamycin

Kerri J. Kinghorn, Sebastian Grönke, Jorge Iván Castillo-Quan et al. · Journal of Neuroscience · 2016 · 157 citations · Full text

Direct Keap1-Nrf2 disruption as a potential therapeutic target for Alzheimer’s disease

Fiona Kerr, Oyinkan Sofola-Adesakin, Dobril Ivanov et al. · PLoS Genetics · 2017 · 140 citations · Full text

Synaptic Transmission, Neurochemical Biomarkers, Alzheimer ’ +28