Kshitij Thakkar

Discovery of 2-[3,5-Dichloro-4-(5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yloxy)phenyl]-3,5-dioxo-2,3,4,5-tetrahydro[1,2,4]triazine-6-carbonitrile (MGL-3196), a Highly Selective Thyroid Hormone Receptor β Agonist in Clinical Trials for the Treatment of Dyslipidemia

Martha J. Kelly, Sherrie Pietranico-Cole, J. Douglas Larigan et al. · Journal of Medicinal Chemistry · 2014 · 205 citations · Full text

Pharmacotherapy, Experimental Pharmacology, Central Thyroid Axis +16

Synthesis and protein-tyrosine kinase inhibitory activity of polyhydroxylated stilbene analogs of piceatannol

Kshitij Thakkar, Robert L. Geahlen, Mark Cushman · Journal of Medicinal Chemistry · 1993 · 144 citations · Full text

Polyhydroxylated Stilbene Analogs, Medicinal Chemistry, Polyphenolics +12

A Novel Oxidative Cyclization of 2'-Hydroxychalcones to 4,5-Dialkoxyaurones by Thallium(III) Nitrate

Kshitij Thakkar, Mark Cushman · The Journal of Organic Chemistry · 1995 · 74 citations

Chemical Measurement, Bioorganic Chemistry, Engineering +14

Preparation and Diastereoselective Birch Reduction−Alkylation of Chiral 3,4-Dihydro-1(2<i>H</i>)-isoquinolinones. Enantiospecific Syntheses and Opioid Receptor Affinities of Several Hydro-2,3- dimethyl-1<i>H</i>-7,12<i>a</i>-methanobenzo[6,7]cycloocta[1,2-<i>c</i>]pyridine-9-ols

Arthur G. Schultz, Timothy J. Guzi, Erika Larsson et al. · The Journal of Organic Chemistry · 1998 · 30 citations

Diastereoselective Birch Reduction−alkylation, Benzyl Bromide, Organic Chemistry +16

A novel oxidative cyclization of 2′-hydroxychalcones to 4-methoxyaurones by thallium (III) nitrate

Kshitij Thakkar, Mark Cushman · Tetrahedron Letters · 1994 · 29 citations

Heterocyclic, Biochemistry, Natural Sciences +6