Aimee L. Crombie - Concepedia

Author

Aimee L. Crombie

Massachusetts Institute of Technology

Also Known As

A. Crombie, Aimee Crombie, Aimee L. Crombie

Publications

988

Citations

H-Index

Concepts

All Affiliations

Massachusetts Institute of Technology Pfizer (United States)

About

Aimee L. Crombie is an author at Massachusetts Institute of Technology specializing in pharmacology, medicine, and medicinal chemistry.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	4	4	207
2	Natural Sciences	3	3	208
3	Chemistry	2	2	192
4	Social Sciences	1	1	72
5	Biochemistry	1	1	16

Aimee L. Crombie

Publications

611

Citations

H-Index

Page 1

	Year	Citations
Structure–Activity Relationships and Discovery of a G Protein Biased μ Opioid Receptor Ligand, [(3-Methoxythiophen-2-yl)methyl]({2-[(9<i>R</i>)-9-(pyridin-2-yl)-6-oxaspiro-[4.5]decan-9-yl]ethyl})amine (TRV130), for the Treatment of Acute Severe Pain Xiaotao Chen, Philip Pitis, Guodong Liu, Journal of Medicinal Chemistry	2013	193
Ring Expansion-Annulation Strategy for the Synthesis of Substituted Azulenes and Oligoazulenes. 2. Synthesis of Azulenyl Halides, Sulfonates, and Azulenylmetal Compounds and Their Application in Transition-Metal-Mediated Coupling Reactions Aimee L. Crombie, John L. Kane, Kevin M. Shea, The Journal of Organic Chemistry Medicinal ChemistryEnantioselective SynthesisRing Expansion-annulation StrategyAzulenylmetal CompoundsHeterocyclic	2004	101
Synthesis of Polycyclic Benzofused Nitrogen Heterocycles via a Tandem Ynamide Benzannulation/Ring-Closing Metathesis Strategy. Application in a Formal Total Synthesis of (+)-FR900482 Xiao Yin Mak, Aimee L. Crombie, Rick Danheiser The Journal of Organic Chemistry Medicinal ChemistryNatural Product SynthesisHeterocyclicAlkene MetathesisNatural Sciences	2011	91
A Ring Expansion−Annulation Strategy for the Synthesis of Substituted Azulenes. Preparation and Suzuki Coupling Reactions of 1-Azulenyl Triflates John L. Kane, Kevin M. Shea, Aimee L. Crombie, Organic Letters	2001	79
Delta opioid receptor agonists are effective for multiple types of headache disorders Laura S. Moye, Alycia F Tipton, Isaac Dripps, Neuropharmacology Cluster HeadacheNeurophysiologyPain MedicineMultiple TypesMedicine	2018	72
TRV0109101, a G Protein-Biased Agonist of the µ-Opioid Receptor, Does Not Promote Opioid-Induced Mechanical Allodynia following Chronic Administration Michael Koblish, Richard W. Carr, Edward R. Siuda, Journal of Pharmacology and Experimental Therapeutics	2017	31
Synthesis and evaluation of azabicyclo[3.2.1]octane derivatives as potent mixed vasopressin antagonists Aimee L. Crombie, Thomas M. Antrilli, Brandon A. Campbell, Bioorganic & Medicinal Chemistry Letters Medicinal ChemistryHeterocyclicMedicineOrganic ChemistryPharmacotherapy	2010	28
Synthesis and biological evaluation of tricyclic anilinopyrimidines as IKKβ inhibitors Aimee L. Crombie, Fuk‐Wah Sum, Dennis Powell, Bioorganic & Medicinal Chemistry Letters Molecular PharmacologyMedicinal ChemistryBiochemistryMedicineNatural Sciences	2010	16

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