Neutralization of SARS-CoV-2 lineage B.1.1.7 pseudovirus by BNT162b2 vaccine–elicited human sera

Alexander Muik, Ann-Kathrin Wallisch, Bianca Sänger, +9

Science

Human SeraViral DiagnosticsImmunologyViral PathogenesisImmunodominance +15

Neutralization of SARS-CoV-2 Omicron by BNT162b2 mRNA vaccine–elicited human sera

Alexander Muik, Bonny Gaby Lui, Ann-Kathrin Wallisch, +14

Science

VaccinationSpike ProteinVaccine DevelopmentBnt162b2 MrnaViral Diagnostics +13

Omicron BA.1 breakthrough infection drives cross-variant neutralization and memory B cell formation against conserved epitopes

Jasmin Quandt, Alexander Muik, Nadine Salisch, +15

Science Immunology

A prefusion SARS-CoV-2 spike RNA vaccine is highly immunogenic and prevents lung infection in non-human primates

Annette B. Vogel, Isis Kanevsky, Ye Che, +58

VaccinationVaccine DevelopmentPrevents Lung InfectionVaccine ResearchImmunology +13

Neutralization of SARS-CoV-2 lineage B.1.1.7 pseudovirus by BNT162b2 vaccine-elicited human sera

Alexander Muik, Ann-Kathrin Wallisch, Bianca Sänger, +8

VaccinationViral EvolutionSpike ProteinVaccine DevelopmentVaccine Target +10

Omicron BA.2 breakthrough infection enhances cross-neutralization of BA.2.12.1 and BA.4/BA.5

Alexander Muik, Bonny Gaby Lui, Maren Bacher, +10

Science Immunology

Humoral ResponseImmunologyOmicron Ba.2Omicron Ba.1Antimicrobial Chemotherapy +15

Exposure to BA.4/5 S protein drives neutralization of Omicron BA.1, BA.2, BA.2.12.1, and BA.4/5 in vaccine-experienced humans and mice

Alexander Muik, Bonny Gaby Lui, Maren Bacher, +28

Science Immunology

Humoral ResponseImmunologyImmunodominanceOmicron Ba.1Immunotherapy +15

Neutralization of SARS-CoV-2 Omicron pseudovirus by BNT162b2 vaccine-elicited human sera

Alexander Muik, Bonny Gaby Lui, Ann-Kathrin Wallisch, +13

World Health OrganizationImmunologyViral PathogenesisImmunodominanceViral Structural Protein +15

BNT162b vaccines are immunogenic and protect non-human primates against SARS-CoV-2

Annette B. Vogel, Isis Kanevsky, Ye Che, +71

VaccinationBnt162b VaccinesVaccine DevelopmentVaccine TargetImmunology +13

Omicron BA.2 breakthrough infection enhances cross-neutralization of BA.2.12.1 and BA.4/BA.5

Alexander Muik, Bonny Gaby Lui, Maren Bacher, +10

Humoral ResponseImmunologyOmicron Ba.2Omicron Ba.1Antimicrobial Chemotherapy +16