Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain AL amyloidosis patient

Paolo Swuec, Francesca Lavatelli, Masayoshi Tasaki, +11

Nature Communications

Mechanism of Ubiquitination and Deubiquitination in the Fanconi Anemia Pathway

Sylvie van Twest, Vincent J. Murphy, Charlotte Hodson, +6

Molecular Cell

GeneticsPhysiologyHematologyFanconi Anemia PathwaySystems Biology +1

Intracerebral Injection of Extracellular Vesicles from Mesenchymal Stem Cells Exerts Reduced Aβ Plaque Burden in Early Stages of a Preclinical Model of Alzheimer’s Disease

Chiara Elia, Matteo Tamborini, Marco Rasile, +9

Cells

DNA binding polarity, dimerization, and ATPase ring remodeling in the CMG helicase of the eukaryotic replisome

Alessandro Costa, Ludovic Renault, Paolo Swuec, +7

eLife

A supramolecular assembly mediates lentiviral DNA integration

Allison Ballandras-Colas, Daniel P. Maskell, Erik Serrao, +11

Science

Hiv-1 InHiv-1 In InhibitorsVirus StructureViral ReplicationSupramolecular Assembly +13

Gating movements and ion permeation in HCN4 pacemaker channels

Andrea Saponaro, Daniel Bauer, M. Hunter Giese, +19

Molecular Cell

The FA Core Complex Contains a Homo-dimeric Catalytic Module for the Symmetric Mono-ubiquitination of FANCI-FANCD2

Paolo Swuec, Ludovic Renault, Aaron J. Borg, +6

Cell Reports

Mass spectrometry characterization of light chain fragmentation sites in cardiac AL amyloidosis: insights into the timing of proteolysis

Francesca Lavatelli, Giulia Mazzini, Stéfano Ricagno, +11

Journal of Biological Chemistry

Cas9 Allosteric Inhibition by the Anti-CRISPR Protein AcrIIA6

Olivier Fuchsbauer, Paolo Swuec, Claire Zimberger, +14

Molecular Cell

Cas9 Allosteric InhibitionMolecular BiologyGenetic EngineeringGene EditingGenome Editing +2

Human RECQ1 helicase-driven DNA unwinding, annealing, and branch migration: Insights from DNA complex structures

A.C.W. Pike, Shivasankari Gomathinayagam, Paolo Swuec, +9

Proceedings of the National Academy of Sciences