Concepedia

Alessandro Costa

AC

49

Publications

4K

Citations

36

H-Index

1982

Active since

Affiliations

The Francis Crick Institute(Current)

Imperial College London

University of California, Berkeley

University of Oxford

Cancer Research UK

Alessandro Costa is an author at The Francis Crick Institute specializing in medicine, molecular biology, and natural sciences.

Top concepts

MedicineMolecular BiologyNatural SciencesStructural BiologyDna ReplicationChromatinMicrobiologyBiophysicsProtein FoldingProtein Assembly

Publications per year

1982–2024

49

Publications

49

The structural basis for MCM2–7 helicase activation by GINS and Cdc45

Alessandro Costa, Ivar Ilves, Nele Tamberg et al. · Nature Structural & Molecular Biology · 2011 · 317 citations · Full text

Mcm2–7 Helicase Activation, Biochemistry, Natural Sciences +4

The mechanism of eukaryotic CMG helicase activation

Max E. Douglas, Ferdos Abid Ali, Alessandro Costa et al. · Nature · 2018 · 278 citations

Protein Assembly, Protein Folding, Natural Sciences +2

A Ctf4 trimer couples the CMG helicase to DNA polymerase α in the eukaryotic replisome

Aline C. Simon, Rajika L. Perera, Frederick van Deursen et al. · Nature · 2014 · 212 citations · Full text

Chromatin, Nucleic Acid Chemistry, Medicine +9

A Structure-Based Mechanism for DNA Entry into the Cohesin Ring

Torahiko L. Higashi, Patrik Eickhoff, Joana S. Sousa et al. · Molecular Cell · 2020 · 172 citations · Full text

Activation of the NLRP3 Inflammasome by Group B Streptococci

Alessandro Costa, Rahul Gupta, Giacomo Signorino et al. · The Journal of Immunology · 2012 · 147 citations · Full text

Il-1β Release, Microbial Pathogens, Innate Immune System +23

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