Patricia Gee

Selective Inhibition of Mutant Isocitrate Dehydrogenase 1 (IDH1) via Disruption of a Metal Binding Network by an Allosteric Small Molecule

Gejing Deng, Junqing Shen, Ming Yin et al. · Journal of Biological Chemistry · 2014 · 137 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +17

Dependence on the Pyrimidine Biosynthetic Enzyme DHODH Is a Synthetic Lethal Vulnerability in Mutant KRAS-Driven Cancers

Malvika Koundinya, Judith Sudhalter, Albane Courjaud et al. · Cell chemical biology · 2018 · 125 citations

Medicine, Cancer Biology, Oncology +16

Identification of Functional Conserved Residues of CTP:glycerol-3-phosphate Cytidylyltransferase

Young‐Seo Park, Patricia Gee, Subramaniam Sanker et al. · Journal of Biological Chemistry · 1997 · 74 citations · Full text

Life Sciences, Biochemistry, Microbiology +9

Vasoinhibitory activity of synthetic peptides from the amino terminus of chromogranin A

R. H. Angeletti, S. Aardal, G. Serck‐Hanssen et al. · Acta Physiologica Scandinavica · 1994 · 72 citations

Life Sciences, Pharmacology, Physiology +15

The Crystal Structure of Choline Kinase Reveals a Eukaryotic Protein Kinase Fold

Daniel Peisach, Patricia Gee, Claudia Kent et al. · Structure · 2003 · 71 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13