Pierre‐Louis Tharaux

Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients

Jérôme Hadjadj, Nader Yatim, Laura Barnabei et al. · Science · 2020 · 3.2K citations · Full text

Life Sciences, Immunology, Infectious Diseases +17

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)¹

Daniel J. Klionsky, Amal Kamal Abdel‐Aziz, Sara Abdelfatah et al. · Autophagy · 2021 · 2.6K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +9

Effect of Tocilizumab vs Usual Care in Adults Hospitalized With COVID-19 and Moderate or Severe Pneumonia

Olivier Hermine, Xavier Mariette, Pierre‐Louis Tharaux et al. · JAMA Internal Medicine · 2020 · 777 citations · Full text

Medicine, Infectious Diseases, Pharmacotherapy +14

Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths

Paul Bastard, Adrian Gervais, Jérémie Rosain et al. · Science Immunology · 2021 · 631 citations · Full text

Life Sciences, Immunology, Infectious Diseases +11

TGF-β activity protects against inflammatory aortic aneurysm progression and complications in angiotensin II–infused mice

Yu Wang, Hafid Ait‐Oufella, Olivier Herbin et al. · Journal of Clinical Investigation · 2010 · 411 citations · Full text

Life Sciences, Immunology, Pathobiology +16