Kayoko Mihara

Neuroprotective Efficacy of the Peroxisome Proliferator-Activated Receptor δ-Selective Agonists in Vitro and in Vivo

Akinori Iwashita, Yuko Muramatsu, Takao Yamazaki et al. · Journal of Pharmacology and Experimental Therapeutics · 2006 · 140 citations

Rational Approaches to Discovery of Orally Active and Brain-Penetrable Quinazolinone Inhibitors of Poly(ADP-ribose)polymerase

Kouji Hattori, Yoshiyuki Kido, Hirofumi Yamamoto et al. · Journal of Medicinal Chemistry · 2004 · 95 citations · Full text

Drug Target, Bioorganic Chemistry, Orally Active +18

Inhibition of arterial thrombosis by a protease-activated receptor 1 antagonist, FR171113, in the guinea pig

Yasuko Kato, Yasuhiro Kita, Yoshimi Hirasawa-Taniyama et al. · European Journal of Pharmacology · 2003 · 94 citations

Inflammation, Thrombosis, Thrombopoiesis +13

Discovery of potent and selective PARP-1 and PARP-2 inhibitors: SBDD analysis via a combination of X-ray structural study and homology modeling

Junya Ishida, Hirofumi Yamamoto, Yoshiyuki Kido et al. · Bioorganic & Medicinal Chemistry · 2005 · 82 citations · Full text

Molecular Docking, Sbdd Analysis, Medicinal Chemistry +12

Pharmacological Characterization of a Novel, Potent Adenosine A1 and A2A Receptor Dual Antagonist, 5-[5-Amino-3-(4-fluorophenyl)pyrazin-2-yl]-1-isopropylpyridine-2(1 H)-one (ASP5854), in Models of Parkinson’s Disease and Cognition

Takuma Mihara, Kayoko Mihara, Junko Yarimizu et al. · Journal of Pharmacology and Experimental Therapeutics · 2007 · 75 citations