Iannis Aifantis

Tet2 Loss Leads to Increased Hematopoietic Stem Cell Self-Renewal and Myeloid Transformation

Kelly Moran-Crusio, Linsey B. Reavie, Alan H. Shih et al. · Cancer Cell · 2011 · 1.3K citations · Full text

Developmental Biology, Medicine, Stem Cell Mobilization +8

The bone marrow microenvironment at single-cell resolution

Anastasia N. Tikhonova, Igor Dolgalev, Hai Hu et al. · Nature · 2019 · 903 citations · Full text

Medicine, Biological Microenvironments, Single-cell Analysis +2

Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression

Luisa Cimmino, Igor Dolgalev, Yubao Wang et al. · Cell · 2017 · 684 citations · Full text

Hematological Malignancy, Medicine, Mixed-phenotype Acute Leukemia +6

Molecular patterns of response and treatment failure after frontline venetoclax combinations in older patients with AML

Courtney D. DiNardo, Ing Soo Tiong, Anna Quaglieri et al. · Blood · 2020 · 628 citations · Full text

ASXL1 Mutations Promote Myeloid Transformation through Loss of PRC2-Mediated Gene Repression

Omar Abdel‐Wahab, Mazhar Adli, Lindsay M. LaFave et al. · Cancer Cell · 2012 · 585 citations · Full text

Hematological Malignancy, Chromatin, Somatic Variant +8