Sodium glucose transporter 2 (SGLT2) inhibition with empagliflozin improves cardiac diastolic function in a female rodent model of diabetes

Javad Habibi, Annayya R. Aroor, James R. Sowers, +8

Cardiovascular Diabetology

Cardiac defects contribute to the pathology of spinal muscular atrophy models

Monir Shababi, Javad Habibi, H. T. Yang, +3

Human Molecular Genetics

Cardiac MuscleHeart FailureGeneticsPathologyDisease Gene Identification +23

Endothelial Mineralocorticoid Receptor Mediates Diet-Induced Aortic Stiffness in Females

Guanghong Jia, Javad Habibi, Annayya R. Aroor, +9

Circulation Research

Glycemic control by the SGLT2 inhibitor empagliflozin decreases aortic stiffness, renal resistivity index and kidney injury

Annayya R. Aroor, Nitin A. Das, Andrea J. Carpenter, +12

Cardiovascular Diabetology

Low-Dose Mineralocorticoid Receptor Blockade Prevents Western Diet–Induced Arterial Stiffening in Female Mice

Vincent G. DeMarco, Javad Habibi, Guanghong Jia, +11

Hypertension

Female MiceObesityMetabolic SyndromeFemoral ArteryMineral Metabolism +14

Uric Acid Promotes Left Ventricular Diastolic Dysfunction in Mice Fed a Western Diet

Guanghong Jia, Javad Habibi, Lixin Ma, +5

Hypertension

NutritionHeart FailureExperimental NutritionDiastolic FunctionOxidative Stress +16

Endothelial Mineralocorticoid Receptor Deletion Prevents Diet-Induced Cardiac Diastolic Dysfunction in Females

Guanghong Jia, Javad Habibi, Vincent G. DeMarco, +10

Hypertension

NutritionHypertensionHeart FailureMetabolic DisorderCardiometabolic Risk +16

Oxidative stress and glomerular filtration barrier injury: role of the renin-angiotensin system in the Ren2 transgenic rat

Adam Whaley‐Connell, Nazif Chowdhury, Melvin R. Hayden, +9

American Journal of Physiology-Renal Physiology

HypertensionRenal PathologyBasement Membrane ThicknessRen2 Transgenic RatOxidative Stress +14

Low-dose spironolactone reduces reactive oxygen species generation and improves insulin-stimulated glucose transport in skeletal muscle in the TG(mRen2)27 rat

Guido Lastra, Adam Whaley‐Connell, Camila Manrique, +7

American Journal of Physiology-Endocrinology and Metabolism

HypertensionSkeletal Muscle TissueReactive Oxygen SpeciesInsulin SignalingOxidative Stress +19

Nebivolol Improves Diastolic Dysfunction and Myocardial Remodeling Through Reductions in Oxidative Stress in the Zucker Obese Rat

Xinli Zhou, Lixin Ma, Javad Habibi, +7

Hypertension

Heart FailureMetabolic RemodelingCardiovascular FunctionInsulin SignalingDiastolic Function +20