1,2,4-Triazole and 1,3,4-oxadiazole analogues: Synthesis, MO studies, in silico molecular docking studies, antimalarial as DHFR inhibitor and antimicrobial activities

Sampark S. Thakkar, Parth Thakor, Hiren Doshi, +1

Bioorganic & Medicinal Chemistry

Mo StudiesMedicinal ChemistryAntiparasitic AgentMedicineNatural Sciences +10

Phytol induces ROS mediated apoptosis by induction of caspase 9 and 3 through activation of TRAIL, FAS and TNF receptors and inhibits tumor progression factor Glucose 6 phosphate dehydrogenase in lung carcinoma cell line (A549)

Parth Thakor, R. B. Subramanian, Sampark S. Thakkar, +2

Biomedicine & Pharmacotherapy

Tumor BiologyTnf ReceptorsChemoprevention StrategyCaspase 9Medicine +10

Benzothiazole analogues: Synthesis, characterization, MO calculations with PM6 and DFT, in silico studies and in vitro antimalarial as DHFR inhibitors and antimicrobial activities

Sampark S. Thakkar, Parth Thakor, Arabinda Ray, +2

Bioorganic & Medicinal Chemistry

Antifungal AgentBenzothiazole AnaloguesBiochemistryAntiparasitic AgentMedicine +5

Novel morpholinoquinoline nucleus clubbed with pyrazoline scaffolds: Synthesis, antibacterial, antitubercular and antimalarial activities

Sharad C. Karad, Vishal B. Purohit, Parth Thakor, +2

European Journal of Medicinal Chemistry

Medicinal ChemistryBiochemistryAntiparasitic AgentNovel Morpholinoquinoline NucleusMedicine +8

The NLRP3 inflammasome: a potential therapeutic target for traumatic brain injury

Tauheed Ishrat, Saifudeen Ismael, HebaA Ahmed, +3

Neural Regeneration Research

Secondary Brain InjuryTraumatic Brain InjuryImmunologyImmune RegulationCell Death +26

Bacillus species (BT42) isolated from Coffea arabica L. rhizosphere antagonizes Colletotrichum gloeosporioides and Fusarium oxysporum and also exhibits multiple plant growth promoting activity

Tekalign Kejela, Vasudev R. Thakkar, Parth Thakor

BMC Microbiology

Synthesis and biological screening of novel 2-morpholinoquinoline nucleus clubbed with 1,2,4-oxadiazole motifs

Sharad C. Karad, Vishal B. Purohit, Rahul P. Thummar, +7

European Journal of Medicinal Chemistry

Medicinal ChemistryBioorganic ChemistryHeterocyclicBiochemistryNovel 2-Morpholinoquinoline Nucleus +8

Extraction and purification of phytol from Abutilon indicum: cytotoxic and apoptotic activity

Parth Thakor, Japan B. Mehta, Ravikumar Patel, +3

RSC Advances

Abutilon IndicumLeaf ExtractPhytotoxicityBotanyIndian System +10

Synthesis, characterization and applications of cubic fluorite cerium oxide nanoparticles: A comprehensive study

Vidhi Pathak, Paras Lad, Anjali B. Thakkar, +3

Results in Surfaces and Interfaces

Maslinic Acid Inhibits Proliferation of Renal Cell Carcinoma Cell Lines and Suppresses Angiogenesis of Endothelial Cells

Parth Thakor, Wenzhe Song, R. B. Subramanian, +3

Journal of Kidney Cancer and VHL

Endothelial CellsChemoprevention StrategyNutraceutical IngredientTumor BiologyPolyphenolics +18