Astrid Janssen

Targeting the beta‐catenin/APC pathway: a novel mechanism to explain the cyclooxygenase‐2‐independent anticarcinogenic effects of celecoxib in human colon carcinoma cells

Thorsten J. Maier, Astrid Janssen, Ronald Schmidt et al. · The FASEB Journal · 2005 · 134 citations

Chemoprevention Strategy, Cell Death, Cancer Biology +18

The anti-proliferative potency of celecoxib is not a class effect of coxibs

Susanne Schiffmann, Thorsten J. Maier, Ivonne Wobst et al. · Biochemical Pharmacology · 2008 · 56 citations

Oncology, Chemoprevention Strategy, Oncogenic Agent +11

Evidence of COX-2 independent induction of apoptosis and cell cycle block in human colon carcinoma cells after S- or R-ibuprofen treatment

Astrid Janssen, Thorsten J. Maier, Susanne Schiffmann et al. · European Journal of Pharmacology · 2006 · 50 citations

Cell Cycle Block, Anti-inflammatory, Medicine +9

Induction of apoptosis by R-flurbiprofen in human colon carcinoma cells: involvement of p53

Sabine Grösch, Karin Schilling, Astrid Janssen et al. · Biochemical Pharmacology · 2005 · 31 citations

Chemoprevention Strategy, Medicine, Apoptosis +8

p53 is important for the anti-proliferative effect of ibuprofen in colon carcinoma cells

Astrid Janssen, Susanne Schiffmann, Kerstin Birod et al. · Biochemical and Biophysical Research Communications · 2007 · 27 citations

Oncology, Medicine, Colorectal Cancer +9