Excess TGF-β mediates muscle weakness associated with bone metastases in mice

David L. Waning, Khalid S. Mohammad, Steven Reiken, +20

Nature Medicine

Bone HealthOrthopaedic SurgeryPhysiologySkeletal BiologyBone Metastases +4

Bioactivity of Turmeric-derived Curcuminoids and Related Metabolites in Breast Cancer

Laura E. Wright, Jen B. Frye, Bhavana Gorti, +2

Current Pharmaceutical Design

Murine models of breast cancer bone metastasis

Laura E. Wright, Penelope D. Ottewell, Nadia Rucci, +5

BoneKEy Reports

Single-Limb Irradiation Induces Local and Systemic Bone Loss in a Murine Model

Laura E. Wright, Jeroen T. Buijs, Hun-Soo Kim, +12

Journal of Bone and Mineral Research

Comparison of Skeletal Effects of Ovariectomy Versus Chemically Induced Ovarian Failure in Mice

Laura E. Wright, Patricia J. Christian, Zelieann Rivera, +4

Journal of Bone and Mineral Research

Curcuminoids Block TGF-β Signaling in Human Breast Cancer Cells and Limit Osteolysis in a Murine Model of Breast Cancer Bone Metastasis

Laura E. Wright, Jennifer B. Frye, Ashley L. Lukefahr, +4

Journal of Natural Products

Breast OncologyHuman GrowthCancer BiologyPthrp SecretionMammary Gland Development +18

Aromatase inhibitor-induced bone loss increases the progression of estrogen receptor-negative breast cancer in bone and exacerbates muscle weakness <i>in vivo</i>

Laura E. Wright, Ahmed Harhash, Wende Kozlow, +9

Oncotarget

Breast OncologyGynecologyOrthopaedic SurgeryOsteoporosisTumor Biology +18

Mechanical suppression of breast cancer cell invasion and paracrine signaling to osteoclasts requires nucleo-cytoskeletal connectivity

Xin Yi, Laura E. Wright, Gabriel M. Pagnotti, +8

Bone Research

Protection of Trabecular Bone in Ovariectomized Rats by Turmeric (<i>Curcuma longa</i> L.) Is Dependent on Extract Composition

Laura E. Wright, Jennifer B. Frye, Barbara N. Timmermann, +1

Journal of Agricultural and Food Chemistry

Decreased Bone Mineral Density in Rats Rendered Follicle-Deplete by an Ovotoxic Chemical Correlates with Changes in Follicle-Stimulating Hormone and Inhibin A

Ashley L. Lukefahr, Jennifer B. Frye, Laura E. Wright, +3

Calcified Tissue International

Animal PhysiologyInhibin ABody CompositionDevelopmental BiologyPhysiology +12