Rapid Single-Step Induction of Functional Neurons from Human Pluripotent Stem Cells

Yingsha Zhang, ChangHui Pak, Yan Han, +13

Neuron

Embryonic Stem CellInduced Pluripotent Stem CellDevelopmental BiologyMedicineInduced Pluripotent Stem Cells +11

Induction of human neuronal cells by defined transcription factors

Zhiping P. Pang, Nan Yang, Thomas Vierbuchen, +8

Nature

Human CellTranscription FactorsMedicineCell BiologyNeural Stem Cell +1

ACTN3 Genotype Is Associated with Human Elite Athletic Performance

Nan Yang, Daniel G. MacArthur, Jason P. Gulbin, +4

The American Journal of Human Genetics

Sport PhysiologyKinesiologyHigh-performance SportExerciseGenetics +4

Generation of pure GABAergic neurons by transcription factor programming

Nan Yang, Soham Chanda, Samuele Marro, +15

Nature Methods

Computational NeuroscienceNeurotransmissionNeuroscienceMolecular NeurobiologySocial Sciences

Direct Lineage Conversion of Terminally Differentiated Hepatocytes to Functional Neurons

Samuele Marro, Zhiping P. Pang, Nan Yang, +5

Cell stem cell

Cell LineageDirect Lineage ConversionDevelopmental BiologyMorphogenesisOrgan Development +5

Loss of ACTN3 gene function alters mouse muscle metabolism and shows evidence of positive selection in humans

Daniel G. MacArthur, Jane T. Seto, Joanna M. Raftery, +12

Nature Genetics

Knockout MouseMuscle PhysiologyMuscle FunctionMolecular PhysiologySkeletal Muscle +10

Generation of oligodendroglial cells by direct lineage conversion

Nan Yang, J. Bradley Zuchero, Henrik Ahlenius, +7

Nature Biotechnology

NeuroregenerationDirect Lineage ConversionDevelopmental BiologyStem Cell ResearchMedicine +2

Association analysis of the ACTN3 R577X polymorphism and complex quantitative body composition and performance phenotypes in adolescent Greeks

Colin N. Moran, Nan Yang, Mark E.S. Bailey, +5

European Journal of Human Genetics

Association AnalysisAdolescent GreeksPhysical ActivityBody CompositionGenotype-phenotype Association +7

ACTN3 genotype influences muscle performance through the regulation of calcineurin signaling

Jane T. Seto, Kate Quinlan, Monkol Lek, +10

Journal of Clinical Investigation

Muscle FunctionCytoskeletonMechanotransductionCalcineurin SignalingCellular Physiology +18

ACTN3 and ACE Genotypes in Elite Jamaican and US Sprinters

Robert A. Scott, Rachael Irving, Laura Irwin, +10

Medicine & Science in Sports & Exercise