Xuyong Chen

Inosine is an alternative carbon source for CD8+-T-cell function under glucose restriction

Tingting Wang, JN Rashida Gnanaprakasam, Xuyong Chen et al. · Nature Metabolism · 2020 · 302 citations · Full text

Glutathione de novo synthesis but not recycling process coordinates with glutamine catabolism to control redox homeostasis and directs murine T cell differentiation

Gaojian Lian, JN Rashida Gnanaprakasam, Tingting Wang et al. · eLife · 2018 · 190 citations · Full text

Glutathione Disulfide, Immunology, Immunologic Mechanism +22

NAD+ supplement potentiates tumor-killing function by rescuing defective TUB-mediated NAMPT transcription in tumor-infiltrated T cells

Yuetong Wang, Fei Wang, Lihua Wang et al. · Cell Reports · 2021 · 103 citations · Full text

Asparagine restriction enhances CD8+ T cell metabolic fitness and antitumoral functionality through an NRF2-dependent stress response

JN Rashida Gnanaprakasam, Bhavana Kushwaha, Lingling Liu et al. · Nature Metabolism · 2023 · 91 citations · Full text

De novo synthesis and salvage pathway coordinately regulate polyamine homeostasis and determine T cell proliferation and function

Ruohan Wu, Xuyong Chen, Siwen Kang et al. · Science Advances · 2020 · 82 citations · Full text