An interleukin-17–mediated paracrine network promotes tumor resistance to anti-angiogenic therapy

Alicia S. Chung, Xiumin Wu, Guanglei Zhuang, +9

Nature Medicine

InflammationCytokineCancer ImmunosurveillanceMedicineImmunology +6

Effector-attenuating Substitutions That Maintain Antibody Stability and Reduce Toxicity in Mice

Megan Lo, Hok Seon Kim, Raymond K. Tong, +14

Journal of Biological Chemistry

Association between HER-2/<b> <i>neu</i> </b> and Vascular Endothelial Growth Factor Expression Predicts Clinical Outcome in Primary Breast Cancer Patients

Gottfried E. Konecny, Y. Gloria Meng, Michael Untch, +10

Clinical Cancer Research

An Fcγ Receptor-Dependent Mechanism Drives Antibody-Mediated Target-Receptor Signaling in Cancer Cells

Nicholas S. Wilson, Becky Yang, Annie Yang, +17

Cancer Cell

Antibody-mediated Target-receptor SignalingCancer ImmunosurveillanceSignal TransductionSignaling PathwayMedicine +13

PlGF Blockade Does Not Inhibit Angiogenesis during Primary Tumor Growth

Carlos Bais, Xiumin Wu, Jenny Yao, +20

Cell

Tumor BiologyAngiogenesisMedicineCell ProliferationVascular Biology +9

TGFβ2 and TGFβ3 isoforms drive fibrotic disease pathogenesis

Tianhe Sun, Zhiyu Huang, Wei‐Ching Liang, +31

Science Translational Medicine

Sustained Brown Fat Stimulation and Insulin Sensitization by a Humanized Bispecific Antibody Agonist for Fibroblast Growth Factor Receptor 1/βKlotho Complex

Ganesh Kolumam, Mark Z. Chen, Raymond K. Tong, +36

EBioMedicine

A Potent Pan-TGFβ Neutralizing Monoclonal Antibody Elicits Cardiovascular Toxicity in Mice and Cynomolgus Monkeys

Mayur S. Mitra, Karla Lancaster, Adeyemi O. Adedeji, +9

Toxicological Sciences

A Therapeutic Anti–VEGF Antibody with Increased Potency Independent of Pharmacokinetic Half-life

Yik A. Yeung, Xiumin Wu, Arthur E. Reyes, +9

Cancer Research

A Neutralizing Anti-gH/gL Monoclonal Antibody Is Protective in the Guinea Pig Model of Congenital CMV Infection

Marcy R. Auerbach, Donghong Yan, Rajesh Vij, +12

PLoS Pathogens