TREATMENT WITH RAPAMYCIN AND MYCOPHENOLIC ACID REDUCES ARTERIAL INTIMAL THICKENING PRODUCED BY MECHANICAL INJURY AND ALLOWS ENDOTHELIAL REPLACEMENT

Clare R. Gregory, Xinfan Huang, Richard E. Pratt, +4

Transplantation

Vascular DiseaseImmunologyPharmacotherapyInflammationThrombosis +14

EPITHELIAL RE-GROWTH IS ASSOCIATED WITH INHIBITION OF OBLITERATIVE AIRWAY DISEASE IN ORTHOTOPIC TRACHEAL ALLOGRAFTS IN NON-IMMUNOSUPPRESSED RATS1

Tuija Ikonen, Tim Brazelton, Gerald J. Berry, +2

Transplantation

OBLITERATIVE AIRWAY DISEASE AFTER HETEROTOPIC TRACHEAL XENOTRANSPLANTATION

Hermann Reichenspurner, V Soni, Michael Nitschke, +6

Transplantation

Antiproliferative effect of rapamycin on growth factor-stimulated human adult lung fibroblasts in vitro may explain its superior efficacy for prevention and treatment of allograft obliterative airway disease in vivo

Rajan V. Nair, Xiaobiao Huang, R. Shorthouse, +4

Transplantation Proceedings

AsthmaSuperior EfficacyAntiproliferative EffectFibrosisMedicine +7

IMMUNOSUPPRESSIVE THERAPIES FOR THE PREVENTION AND TREATMENT OF OBLITERATIVE AIRWAY DISEASE IN HETEROTOPIC RAT TRACHEA ALLOGRAFTS

B. Adams, Gerald J. Berry, Xinfan Huang, +3

Transplantation

Mechanism of action of leflunomide: in vivo uridine administration reverses its inhibition of lymphocyte proliferation.

Hélio Tedesco‐Silva, Wei Cao, R. Shorthouse, +1

PubMed

InflammationMedicineImmunologyVivo Uridine AdministrationPharmacotherapy +2

Treatment with rapamycin blocks arterial intimal thickening following mechanical and alloimmune injury.

Clare R. Gregory, Philip Huie, R. Shorthouse, +4

PubMed

MechanobiologyInflammationSoft Tissue InjuryAlloimmune InjuryVascular Biology +5

Effects of the new and highly active immunosuppressant, rapamycin, on lymphoid tissues and cells in vivo.

Binhai Zheng, R. Shorthouse, Anna Masek, +3

PubMed

InflammationMedicineImmunosuppressive TherapyImmunologyImmune System +8

SP100030 is a novel T-cell-specific transcription factor inhibitor that possesses immunosuppressive activity in vivo.

Mark E. Goldman, Lynn J. Ransone, David W. Anderson, +6

PubMed

Clinical ImmunologyImmunosuppressive ActivityImmune RegulationImmunologyImmunologic Mechanism +7

Infiltrating recipient mesenchymal cells form the obliterative airway disease lesion and dramatically remodel graft tissue in a model of chronic lung rejection

Tim Brazelton, R. Shorthouse, Xiaobiao Huang, +1

Transplantation Proceedings

Acute Lung InjuryInflammatory Lung DiseaseAdvanced Lung DiseaseLung InflammationImmunology +23