IMMUNOSUPPRESSIVE THERAPIES FOR THE PREVENTION AND TREATMENT OF OBLITERATIVE AIRWAY DISEASE IN HETEROTOPIC RAT TRACHEA ALLOGRAFTS

Abstract

Immunosuppressive drug therapy will inhibit airway obliteration, but efficacy sharply diminishes if initiation of treatment is delayed. Efficacy also varies among immunosuppressive compounds, and results indicate those drugs that enable epithelial regrowth most effectively inhibit airway graft obliteration.