Jennifer Kahler

Kinetic Analysis of Epidermal Growth Factor Receptor Somatic Mutant Proteins Shows Increased Sensitivity to the Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, Erlotinib

Kendall D. Carey, Andrew J. Garton, Maria S. Romero et al. · Cancer Research · 2006 · 438 citations

Preclinical Characterization of OSI-027, a Potent and Selective Inhibitor of mTORC1 and mTORC2: Distinct from Rapamycin

Shripad V. Bhagwat, Prafulla C. Gokhale, Andrew P. Crew et al. · Molecular Cancer Therapeutics · 2011 · 200 citations

OSI-930: A Novel Selective Inhibitor of Kit and Kinase Insert Domain Receptor Tyrosine Kinases with Antitumor Activity in Mouse Xenograft Models

Andrew J. Garton, Andrew P. Crew, Maryland Franklin et al. · Cancer Research · 2006 · 80 citations · Full text

Mouse Xenograft Models, Antitumor Activity, Chemoprevention Strategy +18

Discovery of 7-aminofuro[2,3-c]pyridine inhibitors of TAK1: Optimization of kinase selectivity and pharmacokinetics

Keith R. Hornberger, Xin Chen, Andrew P. Crew et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 26 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +8

Enhanced Antitumor Activity of an Anti-5T4 Antibody–Drug Conjugate in Combination with PI3K/mTOR inhibitors or Taxanes

Boris Shor, Jennifer Kahler, Maureen Dougher et al. · Clinical Cancer Research · 2015 · 24 citations