Brooke E. Harcourt

RAGE-Induced Cytosolic ROS Promote Mitochondrial Superoxide Generation in Diabetes

Melinda T. Coughlan, David R. Thorburn, Sally A. Penfold et al. · Journal of the American Society of Nephrology · 2009 · 459 citations · Full text

Glycemic control in diabetes is restored by therapeutic manipulation of cytokines that regulate beta cell stress

Sumaira Z. Hasnain, Danielle J. Borg, Brooke E. Harcourt et al. · Nature Medicine · 2014 · 258 citations

Inflammation, Metabolic Syndrome, Diabetes Management +13

Mapping time-course mitochondrial adaptations in the kidney in experimental diabetes

Melinda T. Coughlan, Tuong-Vi Nguyen, Sally A. Penfold et al. · Clinical Science · 2016 · 163 citations

Mitochondrial Dysfunction, Oxidative Stress, Dynamic Organelles +18

Processed foods drive intestinal barrier permeability and microvascular diseases

Matthew Snelson, Sih Min Tan, Rachel Clarke et al. · Science Advances · 2021 · 147 citations · Full text

Cardiac inflammation associated with a Western diet is mediated via activation of RAGE by AGEs

Christos Tikellis, Merlin C. Thomas, Brooke E. Harcourt et al. · American Journal of Physiology-Endocrinology and Metabolism · 2008 · 129 citations · Full text

Heart Failure, Rage Knockout Mice, Cardiovascular Toxicity +19