Yuanjiu Lei

A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1

Baoyu Zhao, Fenglei Du, Pengbiao Xu et al. · Nature · 2019 · 423 citations · Full text

Life Sciences, Biology, Molecular Biology +10

Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity

Yuanjiu Lei, Jordyn J. VanPortfliet, Yifan Chen et al. · Cell · 2023 · 257 citations · Full text

Life Sciences, Cell Biology, Immunology +17

The molecular basis of tight nuclear tethering and inactivation of cGAS

Baoyu Zhao, Pengbiao Xu, Chesley Marie Rowlett et al. · Nature · 2020 · 247 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +13

Elevated type I interferon responses potentiate metabolic dysfunction, inflammation, and accelerated aging in mtDNA mutator mice

Yuanjiu Lei, Camila Guerra Martinez, Sylvia Torres-Odio et al. · Science Advances · 2021 · 131 citations · Full text

Life Sciences, Genetics, Immunology +17

DDIT3 and KAT2A Proteins Regulate TNFRSF10A and TNFRSF10B Expression in Endoplasmic Reticulum Stress-mediated Apoptosis in Human Lung Cancer Cells

Tianliang Li, Ling Su, Yuanjiu Lei et al. · Journal of Biological Chemistry · 2015 · 130 citations · Full text

Life Sciences, Cell Biology, Oncology +17