Hanzi Sun

Pore-forming activity and structural autoinhibition of the gasdermin family

Jingjin Ding, Kun Wang, Wang Liu et al. · Nature · 2016 · 2.6K citations

Gasdermin Family, Protein Secretion, Biochemistry +2

Discovery of Zanubrutinib (BGB-3111), a Novel, Potent, and Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase

Yunhang Guo, Ye Liu, Nan Hu et al. · Journal of Medicinal Chemistry · 2019 · 332 citations · Full text

A motif in LILRB2 critical for Angptl2 binding and activation

Mi Deng, Zhigang Lu, Junke Zheng et al. · Blood · 2014 · 119 citations

Tislelizumab uniquely binds to the CC′ loop of PD‐1 with slow‐dissociated rate and complete PD‐L1 blockage

Hong Yuan, Yingcai Feng, Hanzi Sun et al. · FEBS Open Bio · 2021 · 70 citations · Full text

Immunology, Cc′ Loop, Molecular Biology +16

BTK Leu528Trp - a Potential Secondary Resistance Mechanism Specific for Patients with Chronic Lymphocytic Leukemia Treated with the Next Generation BTK Inhibitor Zanubrutinib

Sasanka M. Handunnetti, Chloe Pek Sang Tang, Tamia Nguyen et al. · Blood · 2019 · 65 citations