SQANTI: extensive characterization of long-read transcript sequences for quality control in full-length transcriptome identification and quantification

Manuel Tardáguila, Lorena de la Fuente, Cristina Martí, +16

Genome Research

GeneticsMolecular BiologyLong-read Transcript SequencesTranscriptomics TechnologyCorrect Quantification +20

CX3CL1 Promotes Breast Cancer via Transactivation of the EGF Pathway

Manuel Tardáguila, E. Mira, Miguel Ángel García‐Cabezas, +5

Cancer Research

Tumor BiologyBreast OncologyMedicineImmunologyEgf Pathway +12

Notch-regulated miR-223 targets the aryl hydrocarbon receptor pathway and increases cytokine production in macrophages from rheumatoid arthritis patients

Jesús Ogando, Manuel Tardáguila, Andrea Díaz-Alderete, +13

Scientific Reports

SQANTI: extensive characterization of long read transcript sequences for quality control in full-length transcriptome identification and quantification

Manuel Tardáguila, Lorena de la Fuente, Cristina Martí, +16

GeneticsMolecular BiologyTranscriptomics TechnologyGenomicsExtensive Characterization +20

Genetic perturbation of PU.1 binding and chromatin looping at neutrophil enhancers associates with autoimmune disease

Stephen M. Watt, Louella Vasquez, Klaudia Walter, +24

Nature Communications

Genetic associations at regulatory phenotypes improve fine-mapping of causal variants for 12 immune-mediated diseases

Kousik Kundu, Manuel Tardáguila, Alice Mann, +11

Nature Genetics

Causal VariantsGenetic AssociationsImmunogeneticsAutoimmune DiseaseGenotype-phenotype Association +12

tappAS: a comprehensive computational framework for the analysis of the functional impact of differential splicing

Lorena de la Fuente, Ángeles Arzalluz-Luque, Manuel Tardáguila, +13

Genome biology

GeneticsMolecular BiologyTranscriptomics TechnologySplicing VariantTranscriptional Regulation +21

The Polygenic and Monogenic Basis of Blood Traits and Diseases

Dragana Vuckovic, Erik L. Bao, Parsa Akbari, +83

A lovastatin-elicited genetic program inhibits M2 macrophage polarization and enhances T cell infiltration into spontaneous mouse mammary tumors

E. Mira, Lorena Carmona‐Rodríguez, Manuel Tardáguila, +6

Oncotarget

SOD3 improves the tumor response to chemotherapy by stabilizing endothelial HIF-2α

E. Mira, Lorena Carmona‐Rodríguez, Beatriz Pérez‐Villamil, +13

Nature Communications