Exosomal miR-221/222 enhances tamoxifen resistance in recipient ER-positive breast cancer cells

Yifang Wei, Xiaofeng Lai, Shentong Yu, +7

Breast Cancer Research and Treatment

Tumor BiologyBreast OncologyMedicineCancer Cell BiologyExtracellular Microvesicles +8

The pleckstrin homology domain of Bruton tyrosine kinase interacts with protein kinase C.

Libo Yao, Yu Kawakami, Thomas G. Kawakami

Proceedings of the National Academy of Sciences

Mast Cell DisorderImmunologyPleckstrin Homology DomainMolecular BiologyMast Cell +15

Involvement of Bruton's Tyrosine Kinase in FcεRI-dependent Mast Cell Degranulation and Cytokine Production

Daisuke Hata, Yuko Kawakami, Naoki Inagaki, +14

The Journal of Experimental Medicine

N‐Myc downstream‐regulated gene 2 <i>(NDRG2)</i> inhibits glioblastoma cell proliferation

Yanchun Deng, Libo Yao, Ling Chau, +13

International Journal of Cancer

Neuro-oncologyGbm TissuesGene 2GliomaBrain Glioma +12

Tyrosine phosphorylation and activation of Bruton tyrosine kinase upon Fc epsilon RI cross-linking.

Yuko Kawakami, Libo Yao, Tsuyoshi Miura, +3

Molecular and Cellular Biology

Molecular RegulationMast Cell DisorderImmunologyMolecular BiologyImmunologic Mechanism +19

c-Myc-Mediated Epigenetic Silencing of MicroRNA-101 Contributes to Dysregulation of Multiple Pathways in Hepatocellular Carcinoma

Lei Wang, Xiang Zhang, Lintao Jia, +15

Hepatology

C-myc-mediated Epigenetic SilencingPathologyMyc OncogeneEpigeneticsTumor Biology +14

HER2 Interacts With CD44 to Up-regulate CXCR4 via Epigenetic Silencing of microRNA-139 in Gastric Cancer Cells

Wei Bao, Haijing Fu, Qiaosheng Xie, +15

Gastroenterology

Epigenetic SilencingCancer ResearchGastric Cancer CellsMedicineUp-regulate Cxcr4 +7

Notch activation promotes cell proliferation and the formation of neural stem cell-like colonies in human glioma cells

Xueping Zhang, Gang Zheng, Lian Zou, +12

Molecular and Cellular Biochemistry

Neuro-oncologyNeuroregenerationDevelopmental BiologyEpendymaGlioma +10

Pseudogene OCT4-pg4 functions as a natural micro RNA sponge to regulate OCT4 expression by competing for miR-145 in hepatocellular carcinoma

Lei Wang, Zhangyan Guo, Rui Zhang, +8

Carcinogenesis

Molecular BiologyTumor BiologyTranscriptional RegulationStem CellsHuman Hcc +15

Bruton’s tyrosine kinase regulates apoptosis and JNK/SAPK kinase activity

Yuko Kawakami, Toru Miura, Reid P. Bissonnette, +8

Proceedings of the National Academy of Sciences

Mast Cell DisorderTyrosine KinaseApoptosisImmunologyCell Death +17