Brenda M. Luken

High VWF, low ADAMTS13, and oral contraceptives increase the risk of ischemic stroke and myocardial infarction in young women

Helena Andersson, Bob Siegerink, Brenda M. Luken et al. · Blood · 2011 · 149 citations · Full text

Medicine, Cardiology, Obstetrics +12

Conformational activation of ADAMTS13

Kieron South, Brenda M. Luken, James T. B. Crawley et al. · Proceedings of the National Academy of Sciences · 2014 · 139 citations · Full text

Life Sciences, Molecular Biology, Molecular Medicine +15

The spacer domain of ADAMTS13 contains a major binding site for antibodies in patients with thrombotic thrombocytopenic purpura

Brenda M. Luken, Ellen A.M. Turenhout, Janine J. J. Hulstein et al. · Thrombosis and Haemostasis · 2005 · 131 citations

Medicine, Hematology, Pathology +12

An autoantibody epitope comprising residues R660, Y661, and Y665 in the ADAMTS13 spacer domain identifies a binding site for the A2 domain of VWF

Wouter Pos, James T. B. Crawley, Rob Fijnheer et al. · Blood · 2009 · 127 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11

Autoregulation of von Willebrand factor function by a disulfide bond switch

Diego Butera, Freda Passam, Lining Arnold Ju et al. · Science Advances · 2018 · 95 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17