Janine J. J. Hulstein

A novel nanobody that detects the gain-of-function phenotype of von Willebrand factor in ADAMTS13 deficiency and von Willebrand disease type 2B

Janine J. J. Hulstein, Philip G. de Groot, Karen Silence et al. · Blood · 2005 · 149 citations · Full text

Life Sciences, Genetics, Molecular Biology +16

Acute activation of the endothelium results in increased levels of active von Willebrand factor in hemolysis, elevated liver enzymes and low platelets (HELLP) syndrome

Janine J. J. Hulstein, Pieter J. van Runnard Heimel, Arie Franx et al. · Journal of Thrombosis and Haemostasis · 2006 · 131 citations · Full text

Medicine, Hematology, Pathology +17

The spacer domain of ADAMTS13 contains a major binding site for antibodies in patients with thrombotic thrombocytopenic purpura

Brenda M. Luken, Ellen A.M. Turenhout, Janine J. J. Hulstein et al. · Thrombosis and Haemostasis · 2005 · 131 citations

Medicine, Hematology, Pathology +12

β2-Glycoprotein I inhibits von Willebrand factor–dependent platelet adhesion and aggregation

Janine J. J. Hulstein, Peter J. Lenting, Bas de Laat et al. · Blood · 2007 · 127 citations · Full text

Medicine, Biochemistry, Hematology +10

Acute exacerbations of COPD are associated with a prothrombotic state through platelet-monocyte complexes, endothelial activation and increased thrombin generation

Lisa N. van der Vorm, Li Li, Dana Huskens et al. · Respiratory Medicine · 2020 · 33 citations · Full text

Medicine, Immunology, Hemostasis +15