Virginia M. Zaleskas

Molecular Pathogenesis and Therapy of Polycythemia Induced in Mice by JAK2 V617F

Virginia M. Zaleskas, Daniela S. Krause, Katherine Lazarides et al. · PLoS ONE · 2006 · 215 citations · Full text

Medicine, Hematology, Pathobiology +15

Conformational Control Inhibition of the BCR-ABL1 Tyrosine Kinase, Including the Gatekeeper T315I Mutant, by the Switch-Control Inhibitor DCC-2036

Wayne W. Chan, Scott Wise, Michael D. Kaufman et al. · Cancer Cell · 2011 · 207 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Essential role for Stat5a/b in myeloproliferative neoplasms induced by BCR-ABL1 and JAK2V617F in mice

Christoph Walz, Wesam Ahmed, Katherine Lazarides et al. · Blood · 2012 · 158 citations · Full text

Medicine, Hematology, Immunology +11

Switch Pocket Inhibitors of the ABL Tyrosine Kinase: Distinct Kinome Inhibition Profiles and in Vivo Efficacy in Mouse Models of CML and B-Lymphoblastic Leukemia Induced by BCR-ABL T315I

Richard A. Van Etten, Wayne W. Chan, Virginia M. Zaleskas et al. · Blood · 2008 · 27 citations

Medicine, Oncology, Pharmacology +11

DCC-2036: A Novel Switch Pocket Inhibitor of ABL Tyrosine Kinase with Therapeutic Efficacy Against BCR-ABL T315I In Vitro and in a CML Mouse Model.

Richard A. Van Etten, Wayne W. Chan, Virginia M. Zaleskas et al. · Blood · 2007 · 25 citations

Pharmacy, Medicinal Chemistry, Pharmacology +11