Richard G. Carroll

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1

Evanna L. Mills, Dylan G. Ryan, Hiran A. Prag et al. · Nature · 2018 · 1.8K citations

Life Sciences, Biochemistry, Cell Biology +12

Chimeric Receptors Containing CD137 Signal Transduction Domains Mediate Enhanced Survival of T Cells and Increased Antileukemic Efficacy In Vivo

Michael C. Milone, Jonathan D. Fish, Carmine Carpenito et al. · Molecular Therapy · 2009 · 1.2K citations · Full text

Life Sciences, Immunology, Oncology +17

Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases

Elena Pérez, Jianbin Wang, Jeffrey C. Miller et al. · Nature Biotechnology · 2008 · 999 citations

Life Sciences, Molecular Biology, Molecular Genetics +12

Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains

Carmine Carpenito, Michael C. Milone, Raffit Hassan et al. · Proceedings of the National Academy of Sciences · 2009 · 889 citations · Full text

Life Sciences, Immunology, Oncology +17

Cutting Edge: Regulatory T Cells from Lung Cancer Patients Directly Inhibit Autologous T Cell Proliferation

Edward Y. Woo, Heidi Yeh, Christina Chu et al. · The Journal of Immunology · 2002 · 696 citations · Full text

Life Sciences, Immunology, Oncology +16